Name: SR-17018
Brand: Ethos Labs
SKU: EL-7018
Price: 100.00 USD
Availability: OutOfStock

Question 1

What is SR-17018?

Accepted Answer

SR-17018 is a G protein-biased agonist of the mu-opioid receptor (MOR). It was first described by Laura Bohn and colleagues at the Scripps Research Institute in 2017 and has been the subject of seven peer-reviewed publications including Cell and PNAS. It is sold exclusively as an analytical reference standard.

Question 2

What is the CAS number for SR-17018?

Accepted Answer

The freebase form has CAS number 2134602-45-0. The mesylate salt form has CAS 2101845-34-9. Ethos Labs offers freebase and HCl salt forms.

Question 3

What does G protein-biased agonist mean?

Accepted Answer

A biased agonist preferentially activates one intracellular pathway over another at the same receptor. SR-17018 shows strong selectivity for G protein activation with minimal beta-arrestin-2 recruitment, yielding a bias factor of approximately 80-100 relative to DAMGO.

Question 4

Is SR-17018 approved for human use?

Accepted Answer

No. SR-17018 is not approved for human or veterinary use in any jurisdiction. It has only been studied in preclinical models.

Question 5

What forms does Ethos Labs offer?

Accepted Answer

Ethos Labs offers SR-17018 in freebase (CAS 2134602-45-0) and hydrochloride (HCl) salt forms. Both available in 1 gram quantities with ≥97% purity and full COA.